PinnyPeptide

Thymalin vs Vilon

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

Thymalin

Bioregulators

Original Khavinson thymic peptide complex — multi-peptide immunomodulator with 40-year Russian clinical track record.

Peptide B

Vilon

Bioregulators

Khavinson Lys-Glu dipeptide — immunomodulator with documented life-extension activity in mice.

Typical vial

10 mg

Typical dose

5,000-30,000 mcg

Half-life

Variable (peptide complex)

FDA status

Not FDA approved.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Thymalin effects

  • Reported improvement in T-cell numbers (especially CD4+)
  • Improvement in CD4/CD8 ratio
  • Enhanced NK-cell function
  • Reduction in infection rates in immunocompromised patients
  • Long-term observational reduction in mortality (Khavinson 2003 study)
  • Anti-inflammatory effects

Vilon effects

  • Reported immunomodulatory effects
  • Life-extension and tumor-reduction in mouse studies (Khavinson group)
  • Possible telomere-related activity
  • Support of T-cell function in elderly populations
  • Modulation of immune gene expression

Thymalin side effects

  • Generally well-tolerated across 40 years of Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Caution in active autoimmune disease

Vilon side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Caution in active autoimmune disease

Thymalin dosing ranges

Immune support (Russian clinical)

5-30 mg · Once daily IM or SubQ · 5-10 day course, repeated 2-3 times per year

Vilon dosing ranges

Immune support / anti-aging research

1-5 mg · Once daily (SubQ) or sublingual · 10-20 day cycles, repeated 2-3 times per year

Full Thymalin guide → Full Vilon guide →

Thymalin vs Vilon — common questions

What is the difference between Thymalin and Vilon?

Thymalin: Original Khavinson thymic peptide complex — multi-peptide immunomodulator with 40-year Russian clinical track record. Typical dose 5,000-30,000 mcg. Vilon: Khavinson Lys-Glu dipeptide — immunomodulator with documented life-extension activity in mice. Typical dose 1,000-5,000 mcg. Both fall under the Bioregulators category.

Can you stack Thymalin and Vilon?

Stacking Thymalin with Vilon is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, Thymalin or Vilon?

Thymalin is typically dosed: Once daily IM or SubQ for Immune support (Russian clinical). Vilon is typically dosed: Once daily (SubQ) or sublingual for Immune support / anti-aging research.

Are Thymalin and Vilon FDA approved?

Thymalin: Not FDA approved. Vilon: Not FDA approved.

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