Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.
Peptide A
Growth Hormone
The most potent GHRP — strong GH release with documented cardioprotective signaling.
Peptide B
Growth Hormone
FDA-approved GHRH analog for HIV-associated lipodystrophy with potent GH-releasing activity.
Typical vial
5 mg
Typical dose
100 mcg
Half-life
~55 minutes
FDA status
Not FDA approved for any indication.
Typical vial
2 mg
Typical dose
1000-2000 mcg
Half-life
~26 minutes
FDA status
FDA approved. Egrifta (tesamorelin) approved November 2010 f…
Hexarelin effects
Tesamorelin effects
Hexarelin side effects
Tesamorelin side effects
Hexarelin dosing ranges
Short-course GH stimulation
100 mcg · Two to three times daily (SubQ) · 4 weeks maximum, then 4-week break
Combined with CJC-1295 (Mod GRF)
100 mcg of each · Two to three times daily · 4 weeks on / 4 weeks off
Cardioprotective research
1-2 mcg/kg · Per protocol (research-only) · Variable
Tesamorelin dosing ranges
HIV lipodystrophy (FDA approved)
2000 mcg · Once daily (SubQ) · Ongoing as prescribed
Body composition / anti-aging (off-label)
1000-2000 mcg · Once daily · 8-12 weeks
Hexarelin: The most potent GHRP — strong GH release with documented cardioprotective signaling. Typical dose 100 mcg. Tesamorelin: FDA-approved GHRH analog for HIV-associated lipodystrophy with potent GH-releasing activity. Typical dose 1000-2000 mcg. Both fall under the Growth Hormone category.
Stacking Hexarelin with Tesamorelin is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.
Hexarelin is typically dosed: Two to three times daily (SubQ) for Short-course GH stimulation; Two to three times daily for Combined with CJC-1295 (Mod GRF); Per protocol (research-only) for Cardioprotective research. Tesamorelin is typically dosed: Once daily (SubQ) for HIV lipodystrophy (FDA approved); Once daily for Body composition / anti-aging (off-label).
Hexarelin: Not FDA approved for any indication. Tesamorelin: FDA approved. Egrifta (tesamorelin) approved November 2010 for reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Egrifta SV (reformulated single-vial) approved 2019.
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