PinnyPeptide

Cortagen vs Vilon

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

Cortagen

Bioregulators

Khavinson short peptide bioregulator targeting cortical neurons and CNS gene expression.

Peptide B

Vilon

Bioregulators

Khavinson Lys-Glu dipeptide — immunomodulator with documented life-extension activity in mice.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Cortagen effects

  • Reported support of cortical neuron function and gene expression
  • Improvements in memory and attention (Russian observational)
  • Neuroprotection in cerebral ischemia models
  • Possible support for post-stroke and post-concussive recovery
  • Modulation of neuroplasticity-related gene expression

Vilon effects

  • Reported immunomodulatory effects
  • Life-extension and tumor-reduction in mouse studies (Khavinson group)
  • Possible telomere-related activity
  • Support of T-cell function in elderly populations
  • Modulation of immune gene expression

Cortagen side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Possible mild sleep disturbance with late-day dosing

Vilon side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Caution in active autoimmune disease

Cortagen dosing ranges

Cognitive support

1-5 mg · Once daily morning (SubQ) or intranasal · 10-20 day cycles, repeated 2-3 times per year

Vilon dosing ranges

Immune support / anti-aging research

1-5 mg · Once daily (SubQ) or sublingual · 10-20 day cycles, repeated 2-3 times per year

Full Cortagen guide → Full Vilon guide →

Cortagen vs Vilon — common questions

What is the difference between Cortagen and Vilon?

Cortagen: Khavinson short peptide bioregulator targeting cortical neurons and CNS gene expression. Typical dose 1,000-5,000 mcg. Vilon: Khavinson Lys-Glu dipeptide — immunomodulator with documented life-extension activity in mice. Typical dose 1,000-5,000 mcg. Both fall under the Bioregulators category.

Can you stack Cortagen and Vilon?

Stacking Cortagen with Vilon is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, Cortagen or Vilon?

Cortagen is typically dosed: Once daily morning (SubQ) or intranasal for Cognitive support. Vilon is typically dosed: Once daily (SubQ) or sublingual for Immune support / anti-aging research.

Are Cortagen and Vilon FDA approved?

Cortagen: Not FDA approved. Vilon: Not FDA approved.

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