PinnyPeptide

Cardiogen vs Cortagen

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

Cardiogen

Bioregulators

Khavinson short peptide bioregulator targeting cardiac muscle and vascular endothelium.

Peptide B

Cortagen

Bioregulators

Khavinson short peptide bioregulator targeting cortical neurons and CNS gene expression.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Cardiogen effects

  • Reported improvement in myocardial contractility (Russian observational)
  • Possible reduction in age-related cardiac decline
  • Improved exercise tolerance in elderly CAD patients
  • Modulation of cardiac remodeling processes
  • Anti-inflammatory effects in cardiac tissue

Cortagen effects

  • Reported support of cortical neuron function and gene expression
  • Improvements in memory and attention (Russian observational)
  • Neuroprotection in cerebral ischemia models
  • Possible support for post-stroke and post-concussive recovery
  • Modulation of neuroplasticity-related gene expression

Cardiogen side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Should not substitute for proven cardiac therapies

Cortagen side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Possible mild sleep disturbance with late-day dosing

Cardiogen dosing ranges

Cardiac function support

1-5 mg · Once daily (SubQ) or sublingual · 10-20 day cycles, repeated 2-3 times per year

Cortagen dosing ranges

Cognitive support

1-5 mg · Once daily morning (SubQ) or intranasal · 10-20 day cycles, repeated 2-3 times per year

Full Cardiogen guide → Full Cortagen guide →

Cardiogen vs Cortagen — common questions

What is the difference between Cardiogen and Cortagen?

Cardiogen: Khavinson short peptide bioregulator targeting cardiac muscle and vascular endothelium. Typical dose 1,000-5,000 mcg. Cortagen: Khavinson short peptide bioregulator targeting cortical neurons and CNS gene expression. Typical dose 1,000-5,000 mcg. Both fall under the Bioregulators category.

Can you stack Cardiogen and Cortagen?

Stacking Cardiogen with Cortagen is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, Cardiogen or Cortagen?

Cardiogen is typically dosed: Once daily (SubQ) or sublingual for Cardiac function support. Cortagen is typically dosed: Once daily morning (SubQ) or intranasal for Cognitive support.

Are Cardiogen and Cortagen FDA approved?

Cardiogen: Not FDA approved. Cortagen: Not FDA approved.

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