Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.
Peptide A
Longevity
Synthetic pineal tetrapeptide that activates telomerase and modulates melatonin production.
Peptide B
Immune
Thymic peptide with broad immunomodulatory activity, approved in over 35 countries.
Typical vial
10 mg
Typical dose
5000-10000 mcg
Half-life
~30 minutes (short half-life but biological effects persist due to gene expression changes)
FDA status
Not FDA approved for human use. No clinical trials submitted…
Typical vial
5 mg
Typical dose
1000-1600 mcg
Half-life
~2 hours
FDA status
Not FDA approved. Granted orphan drug designation for hepato…
Epithalon effects
Thymosin Alpha-1 effects
Epithalon side effects
Thymosin Alpha-1 side effects
Epithalon dosing ranges
Anti-aging and telomere support
5-10 mg · Once daily (SubQ) · 10-20 days, repeated 1-2 times per year
Thymosin Alpha-1 dosing ranges
Immune modulation
1000-1600 mcg · Twice weekly (SubQ) · 6-12 months
Hepatitis treatment (clinical protocol)
1600 mcg · Twice weekly · 6-12 months
Acute immune support
1600 mcg · Daily for initial phase, then twice weekly · 2-4 weeks acute, then maintenance
Epithalon: Synthetic pineal tetrapeptide that activates telomerase and modulates melatonin production. Typical dose 5000-10000 mcg. Thymosin Alpha-1: Thymic peptide with broad immunomodulatory activity, approved in over 35 countries. Typical dose 1000-1600 mcg. Both fall under the Longevity and Immune categories.
Stacking Epithalon with Thymosin Alpha-1 is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.
Epithalon is typically dosed: Once daily (SubQ) for Anti-aging and telomere support. Thymosin Alpha-1 is typically dosed: Twice weekly (SubQ) for Immune modulation; Twice weekly for Hepatitis treatment (clinical protocol); Daily for initial phase, then twice weekly for Acute immune support.
Epithalon: Not FDA approved for human use. No clinical trials submitted to the FDA. Thymosin Alpha-1: Not FDA approved. Granted orphan drug designation for hepatocellular carcinoma and hepatitis B. Multiple clinical trials conducted but no NDA submitted.
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