PinnyPeptide

Crystagen vs Pancragen

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

Crystagen

Bioregulators

Khavinson short peptide bioregulator targeting thymus / immune cells.

Peptide B

Pancragen

Bioregulators

Khavinson short peptide bioregulator targeting pancreatic tissue and glucose metabolism.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Typical vial

20 mg

Typical dose

1,000-5,000 mcg

Half-life

Short (minutes); biological effect persists via gene-expression modulation

FDA status

Not FDA approved.

Crystagen effects

  • Reported improvement in T-cell numbers and function
  • Restoration of age-related immune decline (Russian observational)
  • Support of thymic function in elderly patients
  • Anti-inflammatory effects
  • Recovery support after severe illness

Pancragen effects

  • Reported support of residual β-cell function
  • Improvements in fasting glucose and HbA1c (Russian observational)
  • Support of exocrine pancreatic function
  • Improvement in digestion in pancreatic insufficiency
  • Modulation of pancreatic gene expression

Crystagen side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Theoretical: caution in active autoimmune disease (immune modulation)

Pancragen side effects

  • Generally well-tolerated in Russian clinical use
  • Mild injection-site reactions
  • Limited Western safety validation
  • Should not substitute for proven diabetes therapies

Crystagen dosing ranges

Immune support

1-5 mg · Once daily (SubQ) or sublingual · 10-20 day cycles, repeated 2-3 times per year

Pancragen dosing ranges

Pancreatic support

1-5 mg · Once daily (SubQ) or sublingual · 10-20 day cycles, repeated 2-3 times per year

Full Crystagen guide → Full Pancragen guide →

Crystagen vs Pancragen — common questions

What is the difference between Crystagen and Pancragen?

Crystagen: Khavinson short peptide bioregulator targeting thymus / immune cells. Typical dose 1,000-5,000 mcg. Pancragen: Khavinson short peptide bioregulator targeting pancreatic tissue and glucose metabolism. Typical dose 1,000-5,000 mcg. Both fall under the Bioregulators category.

Can you stack Crystagen and Pancragen?

Stacking Crystagen with Pancragen is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, Crystagen or Pancragen?

Crystagen is typically dosed: Once daily (SubQ) or sublingual for Immune support. Pancragen is typically dosed: Once daily (SubQ) or sublingual for Pancreatic support.

Are Crystagen and Pancragen FDA approved?

Crystagen: Not FDA approved. Pancragen: Not FDA approved.

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