PinnyPeptide

FTPP-Adipotide vs HGH Fragment 176-191

Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.

Peptide A

FTPP-Adipotide

Weight Management

Vasculature-targeting peptide that selectively destroys adipose blood vessels.

Peptide B

HGH Fragment 176-191

Weight Management

The unmodified C-terminal fragment of growth hormone — the original lipolytic peptide.

Typical vial

5 mg

Typical dose

Per kg dosing (research-only) mcg

Half-life

~hours

FDA status

Not FDA approved.

Typical vial

5 mg

Typical dose

250-500 mcg

Half-life

~30 minutes

FDA status

Not FDA approved. Distinct from AOD-9604, which holds GRAS s…

FTPP-Adipotide effects

  • Selective destruction of white adipose tissue vasculature
  • Rapid weight and fat loss in primate models
  • Improved insulin sensitivity
  • Brown adipose tissue largely spared
  • Mechanism distinct from lipolytic / appetite-suppressing peptides

HGH Fragment 176-191 effects

  • Stimulates lipolysis (fat breakdown) in adipose tissue
  • Inhibits lipogenesis (new fat formation)
  • Does not bind the GH receptor
  • Does not raise IGF-1 or affect blood glucose
  • Targets stubborn / subcutaneous fat in cut-phase protocols

FTPP-Adipotide side effects

  • Renal toxicity (prohibitin expressed in kidney vasculature) — significant safety concern
  • Possible damage to other prohibitin-expressing vascular beds
  • Injection-site reactions
  • Limited human safety data
  • Acute inflammatory response from adipose vascular death

HGH Fragment 176-191 side effects

  • Injection-site irritation or redness
  • Occasional headache
  • Mild fatigue at the start of a cycle (rare)
  • Transient flushing

FTPP-Adipotide dosing ranges

Animal research (rhesus monkey model)

0.43 mg/kg · Daily SubQ × 28 days · Per published protocol

Human self-experimentation

Not recommended · — · —

HGH Fragment 176-191 dosing ranges

Fat loss / body recomposition

250-500 mcg · Once daily, morning, on an empty stomach (SubQ) · 8-12 weeks

Split-dose protocol for stubborn fat

250 mcg · Twice daily (morning + pre-cardio), fasted · 8-12 weeks

Full FTPP-Adipotide guide → Full HGH Fragment 176-191 guide →

FTPP-Adipotide vs HGH Fragment 176-191 — common questions

What is the difference between FTPP-Adipotide and HGH Fragment 176-191?

FTPP-Adipotide: Vasculature-targeting peptide that selectively destroys adipose blood vessels. Typical dose Per kg dosing (research-only) mcg. HGH Fragment 176-191: The unmodified C-terminal fragment of growth hormone — the original lipolytic peptide. Typical dose 250-500 mcg. Both fall under the Weight Management category.

Can you stack FTPP-Adipotide and HGH Fragment 176-191?

Stacking FTPP-Adipotide with HGH Fragment 176-191 is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.

Which is dosed more frequently, FTPP-Adipotide or HGH Fragment 176-191?

FTPP-Adipotide is typically dosed: Daily SubQ × 28 days for Animal research (rhesus monkey model); — for Human self-experimentation. HGH Fragment 176-191 is typically dosed: Once daily, morning, on an empty stomach (SubQ) for Fat loss / body recomposition; Twice daily (morning + pre-cardio), fasted for Split-dose protocol for stubborn fat.

Are FTPP-Adipotide and HGH Fragment 176-191 FDA approved?

FTPP-Adipotide: Not FDA approved. HGH Fragment 176-191: Not FDA approved. Distinct from AOD-9604, which holds GRAS status as a food additive.

Related peptide comparisons

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