Side-by-side comparison: effects, dosing ranges, side effects, regulatory status, and reconstitution.
Peptide A
Muscle Growth
Endogenous activin/myostatin binding protein — the gene-therapy myostatin inhibitor.
Peptide B
Growth Hormone
A locally-acting IGF-1 splice variant released by muscle in response to mechanical load.
Typical vial
1 mg
Typical dose
100-300 mcg
Half-life
~30 minutes (recombinant); years (AAV expression)
FDA status
Not FDA approved as recombinant protein. AAV-Follistatin gen…
Typical vial
2 mg
Typical dose
200-400 mcg
Half-life
~5-7 minutes (MGF); ~2-3 days (PEG-MGF)
FDA status
Not FDA approved for any indication.
Follistatin effects
MGF (Mechano Growth Factor) effects
Follistatin side effects
MGF (Mechano Growth Factor) side effects
Follistatin dosing ranges
Research / muscle hypertrophy (recombinant)
100-300 mcg · Daily (SubQ) · 10-30 days per cycle
AAV gene therapy (clinical)
Single high-titer AAV infusion · One-time · Durable expression (years)
MGF (Mechano Growth Factor) dosing ranges
Localized muscle repair (non-pegylated)
200-300 mcg per site · Post-workout, into the worked muscle (intramuscular) · 3-4 weeks per cycle
Systemic muscle recovery (PEG-MGF)
200-400 mcg · Twice weekly (SubQ) · 4-6 weeks per cycle
Follistatin: Endogenous activin/myostatin binding protein — the gene-therapy myostatin inhibitor. Typical dose 100-300 mcg. MGF (Mechano Growth Factor): A locally-acting IGF-1 splice variant released by muscle in response to mechanical load. Typical dose 200-400 mcg. Both fall under the Muscle Growth and Growth Hormone categories.
Stacking Follistatin with MGF (Mechano Growth Factor) is a protocol-design question best raised with a clinician — it depends on your goal, current bloodwork, and whether both peptides target overlapping mechanisms. Both peptides should be tracked independently with separate injection sites and timing. PinnyPeptide supports multi-peptide stacks with automatic injection site rotation.
Follistatin is typically dosed: Daily (SubQ) for Research / muscle hypertrophy (recombinant); One-time for AAV gene therapy (clinical). MGF (Mechano Growth Factor) is typically dosed: Post-workout, into the worked muscle (intramuscular) for Localized muscle repair (non-pegylated); Twice weekly (SubQ) for Systemic muscle recovery (PEG-MGF).
Follistatin: Not FDA approved as recombinant protein. AAV-Follistatin gene therapy in clinical trials. MGF (Mechano Growth Factor): Not FDA approved for any indication.
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